Patient history: Name: Elvira Age: 56 gender :Female Medical history : ASA I Dental history: patient receives implants at a Chilean university and arrives to be rehabilitated Reason for consultation: I need to finish my treatment Initial X-ray Diagnosis: • Maxillary and mandibular partial edentulousness • Periodontal diagnosis: Stage I chronic periodontitis, localized, Grade A.(Caton,2017) Treatment: Implant-assisted rehabilitation ad-modum all on six open tray impression transfer splint bar test Articulation test - occlusion termination final x-ray

Patient history: Name: Valentina Age: 31 gender : Female Medical history : ASA I Dental history: patient with p 1.5 fractured due to over-instrumentation in endodontic treatment Reason for consultation: I need an implant so that the space cannot be seen when removing the broken tooth. Initial X-ray diagnostic wax-up cone beam Diagnosis: • Maxillary and mandibular partial edentulousness • Periodontal diagnosis: Stage I chronic periodontitis, localized, Grade A.(Caton,2017) • Dental Diagnosis: Localized hypoplastic non-syndromic amelogenesis imperfecta. (Nusier,2004) • ADM: number – size – position. Relevant clinical situations: • Fine Gingival Biotype. • Class II (Seibert,1983) and Mild (Allen,1985) alveolar ridge collapse. • Thickness of the vestibular bone table with respect to the root of p 1.5: coronal: 1.67 mm- apical: 1.02 mm Treatment: Immediate implant surgery (submerged) – post extraction p 1.5 ISIII Active Neobiotech Implant 4.0 mm x 13 mm ROG: InterOSS Demineralized Bovine Bone without organic matrix 0.5 gr final x-ray

Patient history: Name: Pamela Age: 34 Female gender Medical history : ASA I Dental history: patient with recently completed orthodontics requests IOI to complete their comprehensive treatment Reason for consultation: I want to complete my orthodontic treatment Initial X-ray diagnostic wax-up Cone Beam Diagnosis: • Maxillary and mandibular partial edentulousness • Periodontal diagnosis: Gingivitis associated only with plaque (Caton, 2017) Relevant clinical situations • Fine Gingival Biotype. • Collapse of the alveolar ridge Class III (Seibert,1983) Treatment plan: ISII Active-Regular Neobiotech implant ROG: InterOSS Demineralized Bovine Bone without organic matrix 0.5 gr Collagen membrane 15 x 30 final x -ray

Patient history: Name: Charles Age: 62 Gender: male Medical history : ASA I – heavy smoker Dental history: patient with pfu at p 2.4 dislodged and fractured, p 2.5 root remnant. Reason for consultation: a tooth was broken and I want an implant in that sector Initial X-ray diagnostic wax-up cone beam p 2.4 cone beam 2.5 Diagnosis: • Maxillary and mandibular partial teeth. • Periodontal diagnosis: Plaque-induced gingivitis in the reduced periodontium. Modified by tobacco (Caton, 2017). Relevant clinical situations • Heavy Smoker. • Thick Gingival Biotype. • Horizontal and vertical alveolar ridge deficiency in tooth area 2.6. Treatment plan: Immediate implant surgery – post extraction p 2.4 and p 2.5 with neo naviguide ISIII Active Neobiotech Implant ROG: Allograft bone graft 1.5 cc (Regenoss cortical bone and cancellous bone), collagen membrane 15x10. Digital planning with blue sky plan surgical guide test carved surgical beds implant installation great torque achieved Implants installed to perform ROG final x -ray

Patient history: Name: Nora Age: 50 Gender: Female Medical history : ASA I – heavy smoker – depression Dental history: patient loses all of his teeth due to lack of economic resources, currently looking for a more comfortable and aesthetic solution Reason for consultation: my prostheses move a lot, I need something firm Initial X-ray – initial clinic cone beam Diagnostic wax-up - Occlusion test – neutral canine and molar occlusion Occlusion test – profile and lip support reestablished Diagnosis: • Maxillary and mandibular total edentulousness Relevant clinical situations • Class III ridge collapse (Seibert,1983)- Moderate (Allen,1985). • Heavy Smoker. Treatment plan: Regularization of the alveolar ridge in the maxilla and mandible. Surgery of implants in the maxilla: 4 (2 straight and 2 angled) (all on four) + osseodensification with versah burs Jaw implant surgery: 4 (2 straight and 2 angled) ISIII Active Neobiotech implants ROG: InterOSS Demineralized Bovine Bone without organic matrix 1 gr Collagen membrane 15 x 30 Final rehabilitation type ad modum upper and lower Semi-strict surgical guide - prosthetic duplicate - test on patient Surgery – initial center pin Surgery – upper semi-strict guide positioning Neobiotech protocol + osseodensification with versah burs osseodensification with versah burs final x-ray Beginning to rehabilitate the jaw - 4 months later open tray impression bar test mandibular occlusion test final smile rehabilitative control x-ray

Patient history: Name: Rodrigo Age: 44 Gender: male Medical history : ASA I – heavy smoker Dental history: failed endodontic treatment, chambered floor perforation p 3.6 Reason for consultation: I need a new tooth initian radiograph diagnostic wax-up Diagnosis: • Maxillary and mandibular total teeth • Periodontal diagnosis: Plaque-induced gingivitis in the reduced periodontium. Modified by tobacco (Caton, 2017) Relevant clinical situations • Bone quality classification: Type II (Lekholm and Zarb,1985) • Anatomical Classification: Type I (Cawood and Howell, 1988) • Heavy Smoker. • Fine Gingival Biotype. • Deficient attached gingiva due to vestibular p 3.6 Treatment plan: Type I immediate implant surgery (The Third ITI Consensus Conference. Ha¨mmerle et al. 2004) –post extraction p 3.6 ISIII Active Neobiotech Implant 4.0 mm x 11.5 mm Alveolar preservation: Bone graft Allograft 1cc (Alpha-Bio GRAFT cortical bone and lyophilized cancellous bone). PRF Implant-assisted Pfu Semi-strict surgical guide - scientifically endorsed surgical technique Neobiotech surgical protocol and semi-strict guide Position is confirmed, prosthetically guided, extraction ISIII implant – progressive torque ROG: Allograft 1cc (Alpha-Bio GRAFT cortical bone and lyophilized cancellous bone)- healing abutament 6.0 x 2 mm and L-PRF Immediate radiographic control Surgical control at 7 days control 1 month Control 3rd month

Patient history: Name: Claude - Age: 78 - Gender: male Medical history : HTA ASA II Dental history: loss of multiple teeth without being able to use a removable upper prosthesis due to the palatal torus, producing posterior lifting, leaving no occlusal support for feeding. Reason for consultation: I want something fixed to be able to feed myself. Diagnosis: • Maxillary and mandibular partial edentulousness • Periodontal diagnosis: Stage III chronic periodontitis, localized, Grade A.(Caton,2017) Relevant clinical situations • Fine Gingival Biotype. • Collapse of the ridge Class II (Seibert,1983) Moderate (Allen,1985). • Upper lip line: Tall smile. • Ridge shape (Coscolla Rodriguez): U shape: Palatal and buccal faces in parallel position, provides a good "occlusal surface" and is the most favorable. • Lekholm and Zarb (1985) Classification: Class C: Advanced anterior resorption of residual alveolar bone. • Atwood Classification: Class V: Low well rounded in the anterior zone.- Class III: High well rounded in the right post zone. treatment plan: Multiple implants, All on Four technique with Neobiotech ISIII active implants + osseodensification with versah drills in posterior beds, ROG (Botis): Bone graft: non-resorbable xenograft (demineralized Bovine Bone without organic matrix) and Jason membrane stabilized with resorbable suture. Implant with immediate load (temporal-definitive fixed) using upper prosthesis, installation of straight and angled pillars for temporary multiunic. prosthetic duplicate and semi-strict surgical guide definitive temporary prosthesis Final hybrid prosthesis installed.